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Review
. 2005 Feb;8(1):54-9.
doi: 10.1016/j.mib.2004.12.001.

Interaction of uropathogenic Escherichia coli with host uroepithelium

Andrew L Kau  1 , David A Hunstad, Scott J Hultgren
Affiliations
Review

Interaction of uropathogenic Escherichia coli with host uroepithelium

Andrew L Kau et al. Curr Opin Microbiol. 2005 Feb.

Abstract

Investigation into the pathogenesis of Escherichia coli urinary tract infection has provided numerous insights into the mechanisms by which bacteria adhere, grow and persist in association with host tissue. Many molecular details concerning the interaction of these bacteria with their host have been elucidated, and the murine model of cystitis has generated a new paradigm by which acute and recurrent urinary tract infections may proceed. These advances could potentially result in the development of novel vaccines and therapies for this very costly disease.

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