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Review
. 2005 Jun;67(5):592-9.
doi: 10.1007/s00253-005-1917-2. Epub 2005 Feb 8.

Microbial production and applications of chiral hydroxyalkanoates

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Review

Microbial production and applications of chiral hydroxyalkanoates

Guo-Qiang Chen et al. Appl Microbiol Biotechnol. 2005 Jun.

Abstract

Polyhydroxyalkanoates (PHA) are a family of polyesters consisting of over 150 chiral hydroxyalkanoic acids (HA). This paper reviews the physiological functions of (R)-3-hydroxybutyric acid (3HB) and (R)-4-hydroxybutyric acid and summarizes the technologies developed to produce various HA [3HB, (R)-3-hydroxyoctanoic acid, (R)-3-hydroxydecanoic acid, etc.] and the applications of chiral HA. Their outlooks and perspectives are discussed.

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