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. 2005 Feb 9:2:4.
doi: 10.1186/1742-4682-2-4.

Single cell studies of the cell cycle and some models

J M Mitchison  1
Affiliations

Single cell studies of the cell cycle and some models

J M Mitchison. Theor Biol Med Model. .

Abstract

Analysis of growth and division often involves measurements made on cell populations, which tend to average data. The value of single cell analysis needs to be appreciated, and models based on findings from single cells should be taken into greater consideration in our understanding of the way in which cell size and division are co-ordinated. Examples are given of some single cell analyses in mammalian cells, yeast and other microorganisms. There is also a short discussion on how far the results are in accord with simple models.

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Figures

Figure 1
Figure 1
Modes of growth in cell length of wild-type and wee1 mutant cells of fhe fission yeast Schizosaccharomyces pombe, after Sweiczer et al. (1996)
Figure 2
Figure 2
Growth through one cycle of individual Amoeba, after Prescott (1976)
See this image and copyright information in PMC

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