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Clinical Trial
. 2005 Jul;43(7):408-16.
doi: 10.1038/sj.sc.3101729.

A prospective assessment of mortality in chronic spinal cord injury

E Garshick  1 , A Kelley, S A Cohen, A Garrison, C G Tun, D Gagnon, R Brown
Affiliations
Clinical Trial

A prospective assessment of mortality in chronic spinal cord injury

E Garshick et al. Spinal Cord. 2005 Jul.

Abstract

Study design: Prospective mortality study.

Objective: To assess the relationship between comorbid medical conditions and other health-related factors to mortality in chronic spinal cord injury (SCI).

Setting: Boston, MA, USA.

Methods: Between 1994 and 2000, 361 males >/=1 year after injury completed a respiratory health questionnaire and underwent pulmonary function testing. Cause-specific mortality was assessed over a median of 55.6 months (range 0.33-74.4 months) through 12/31/2000 using the National Death Index.

Results: At entry, mean (+/-SD) age was 50.6+/-15.0 years (range 23-87) and years since injury was 17.5+/-12.8 years (range 1.0-56.5). Mortality was elevated (observed/expected deaths=37/25.1; SMR=1.47; 95% CI=1.04-2.03) compared to US rates. Risk factors for death were diabetes (RR=2.62; 95% CI=1.19-5.77), heart disease (RR=3.66; 95% CI=1.77-7.78), reduced pulmonary function, and smoking. The most common underlying and contributing causes of death were diseases of the circulatory system (ICD-9 390-459) in 40%, and of the respiratory system in 24% (ICD-9 460-519).

Conclusions: These results suggest that much of the excess mortality in chronic SCI is related to potentially treatable factors. Recognition and treatment of cardiovascular disease, diabetes, and lung disease, together with smoking cessation may substantially reduce mortality in chronic SCI.

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References

    1. Samsa GP, Patrick CH, Feussner JR. Long-term survival of veterans with traumatic spinal cord injury. Arch Neurol. 1993;50:909–914. - PubMed
    1. DeVivo MJ, Stover SL. Long-term survival and causes of death. In: Stover SL, DeLisa JA, Whiteneck GG (eds). Spinal Cord Injury: Clinical Outcomes from the Model Systems Aspen Publishers: Gaithersburg, MD 1995, pp 289–316.
    1. Mesard L, Carmody A, Mannarino E, Ruge D. Survival after spinal cord trauma. A life table analysis. Arch Neurol. 1978;35:78–83. - PubMed
    1. Soden RJ, et al. Causes of death after spinal cord injury. Spinal Cord. 2000;38:604–610. - PubMed
    1. Hartkopp A, Bronnum-Hansen H, Seidenschnur AM, Biering-Sorensen F. Survival and cause of death after traumatic spinal cord injury. A long-term epidemiological survey from Denmark. Spinal Cord. 1997;35:76–85. - PubMed

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