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Case Reports
. 2005 Feb;24(2):153-5.
doi: 10.1007/s10096-005-1289-7.

Long-term survival and interruption of HAART in HIV-related pulmonary hypertension

A S Zinkernagel  1 , J von Overbeck, M Opravil, R Jenni, R Speich, N J Mueller
Affiliations
Free article
Case Reports

Long-term survival and interruption of HAART in HIV-related pulmonary hypertension

A S Zinkernagel et al. Eur J Clin Microbiol Infect Dis. 2005 Feb.
Free article

Abstract

Reported here is a case of a patient with pulmonary arterial hypertension related to HIV (PAHRH) in which lipodystrophy necessitated interruption of highly active antiretroviral therapy (HAART) and long-term survival was the outcome. Although previous studies have suggested antiretroviral therapy may benefit patients with this rare complication of HIV infection, no worsening of PAHRH was observed when HAART was interrupted. Clinical and echocardiographic parameters remained stable during 7 months of follow up. In cases in which HAART is associated with relevant toxicity, interruption of HAART in patients with PAHRH can be considered, but should be used only if no alternatives are available. Close follow-up is warranted.

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