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Case Reports
. 2005 Mar;96(3):902-5.
doi: 10.1016/j.ygyno.2004.12.001.

Activity of bevacizumab (rhuMAB VEGF) in advanced refractory epithelial ovarian cancer

Bradley J Monk  1 , David C Choi, Gordon Pugmire, Robert A Burger
Affiliations
Case Reports

Activity of bevacizumab (rhuMAB VEGF) in advanced refractory epithelial ovarian cancer

Bradley J Monk et al. Gynecol Oncol. 2005 Mar.

Abstract

Background: Angiogenesis is pivotal in the development and progression of ovarian cancer and is an ideal candidate for novel treatment approaches.

Case: A case of advanced, recurrent and refractory serous carcinoma is presented that responded to bevacizumab 15 mg/m2 intravenously every 3 weeks after failing eleventh line cytotoxic chemotherapy and radiation. An objective durable response lasting at least 5 months was documented.

Conclusion: Bevacizumab has activity in epithelial ovarian carcinoma and larger scale trials are indicated.

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