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. 2005 Jan;31(1):156-62.
doi: 10.1016/j.jcrs.2004.10.044.

Determining in vivo biomechanical properties of the cornea with an ocular response analyzer

David A Luce  1
Affiliations

Determining in vivo biomechanical properties of the cornea with an ocular response analyzer

David A Luce. J Cataract Refract Surg. 2005 Jan.

Abstract

Purpose: To study the results of an ocular response analyzer (ORA) to determine the biomechanical properties of the cornea and their relationship to intraocular pressure (IOP).

Setting: Reichert Inc., Depew, New York, USA.

Methods: The ORA (Reichert) makes 2 essentially instantaneous applanation measurements that permit determination of corneal and IOP effects.

Results: Measurements of several populations indicate that corneal hysteresis, a biomechanical measure, varied over a dynamic range of 1.8 to 14.6 mm Hg and was only weakly correlated with corneal thickness (r(2)=0.12); this is related to the observation that some subjects with relatively thick corneas have less-than-average corneal hysteresis. Corneal hysteresis changes diurnally, presumably as a result of hydration changes. Keratoconus, Fuchs' dystrophy, and post-LASIK patients demonstrated low corneal hysteresis.

Conclusion: The corneal hysteresis biomechanical measure may prove valuable for qualification and predictions of outcomes of refractive surgery and in other cases in which corneal biomechanics are important.

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