Review
doi: 10.1016/j.cub.2005.02.008.
Checkpoint signalling: Mad2 conformers and signal propagation
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- PMID: 15723780
- DOI: 10.1016/j.cub.2005.02.008
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Review
Checkpoint signalling: Mad2 conformers and signal propagation
Curr Biol.
.
Free article
Abstract
The spindle checkpoint protein Mad2 has a tendency to form multimers and adopts at least two structural conformations. New work highlights the importance of the Mad2-Mad2 interaction, and suggests how spindle checkpoint signals are propagated away from kinetochores.
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