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Review
. 2005 Feb 22;15(4):R139-41.
doi: 10.1016/j.cub.2005.02.015.

TOR signaling: an odyssey from cellular stress to the cell growth machinery

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Free article
Review

TOR signaling: an odyssey from cellular stress to the cell growth machinery

Robert T Abraham. Curr Biol. .
Free article

Abstract

The target of rapamycin (TOR) protein kinase is centrally involved in the coordination of cell growth and proliferation with the availability of growth factors and nutrients. Two recent reports have illuminated a mechanism whereby hypoxic stress dampens TOR signaling in metazoan cells.

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