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. 1992 Apr;34(4):285-95.
doi: 10.1111/j.1469-8749.1992.tb11432.x.

Relation between cerebral oxidative metabolism following birth asphyxia, and neurodevelopmental outcome and brain growth at one year

S C Roth  1 , A D Edwards, E B Cady, D T Delpy, J S Wyatt, D Azzopardi, J Baudin, J Townsend, A L Stewart, E O Reynolds
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Relation between cerebral oxidative metabolism following birth asphyxia, and neurodevelopmental outcome and brain growth at one year

S C Roth et al. Dev Med Child Neurol. 1992 Apr.

Abstract

Studies of cerebral oxidative metabolism were carried out by phosphorous magnetic resonance spectroscopy during the first week of life in 52 infants with clinical and/or biochemical evidence of birth asphyxia. 15 infants died and the 37 survivors were assessed by a wide range of neurodevelopmental tests at one year of age. The minimum recorded values for cerebral phosphocreatine/inorganic phosphate concentration ratio (an index of oxidative metabolism) were related to outcome. The results showed a significant relation between the extent of derangement of oxidative metabolism and the severity of adverse outcomes, including death, neurodevelopmental impairment and reduced head growth.

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  • Birth asphyxia.
    Bax M. Bax M. Dev Med Child Neurol. 1992 Apr;34(4):283-4. doi: 10.1111/j.1469-8749.1992.tb11431.x. Dev Med Child Neurol. 1992. PMID: 1572513 No abstract available.

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