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. 2005 Mar 3;7(5):771-4.
doi: 10.1021/ol040066p.

Addition of carbamoylsilanes to electrophilically substituted alkenes. Preparation of beta-functionalized tertiary amides

Robert F Cunico  1 , Adalie Rodriguez Motta
Affiliations

Addition of carbamoylsilanes to electrophilically substituted alkenes. Preparation of beta-functionalized tertiary amides

Robert F Cunico et al. Org Lett. .

Abstract

The Si-C bond of N,N-dimethylcarbamoylsilanes added regiospecifically to the C=C bond of electrophilically functionalized alkenes to afford beta-silyl-beta-functionalized amides. Carbonyl addition products were formed when hindered alkenic esters were used. [reaction: see text]

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