Salmonellosis: an epidemiologic study
- PMID: 15729958
Salmonellosis: an epidemiologic study
Abstract
Background: Salmonella species commonly produce acute gastroenteritis. The clinical course may be affected by factors such as age, immunosuppression, and underlying disorders.
Objectives: To investigate clinical and laboratory differences in the infected population and the risk of complications according to the different age groups.
Methods: The records of 295 patients with positive cultures for Salmonella were divided into six age groups and reviewed retrospectively for the years 1994-1997. Demographic, clinical and laboratory data, extraintestinal manifestations, underlying disorders, organism source, and susceptibilty to antibiotics were analyzed.
Results: We found that 88.5% were only stool positive, 9.2% had positive blood cultures, and 2.4% were positive in both blood and stool; 3.6% were found to have underlying disorders. Anemia, disturbed liver function tests and hypoalbuminemia were the most common pathologic laboratory findings. Salmonella serogroups B and D were isolated most frequently. The rate of positive blood cultures increased significantly during the years, as did resistance to ampicillin and trimethoprimsulfamethoxazole. Salmonella infection has two peaks of incidence: at ages 1-5 and 15-65 years. Bacteremia was prominent in the extreme ages.
Conclusions: Salmonella infection has a different clinical presentation in different age groups. The significant increase in the rate of bacteremia in the extreme age groups necessitates a different attitude and management for these heterogeneous patient populations.
Similar articles
-
Change of serotype pattern of Group D non-typhoidal Salmonella isolated from pediatric patients in southern Taiwan.J Microbiol Immunol Infect. 2007 Jun;40(3):234-9. J Microbiol Immunol Infect. 2007. PMID: 17639164
-
Epidemiologic attributes of invasive non-typhoidal Salmonella infections in Michigan, 1995--2001.Int J Infect Dis. 2008 Mar;12(2):176-82. doi: 10.1016/j.ijid.2007.06.006. Epub 2007 Sep 21. Int J Infect Dis. 2008. PMID: 17889584
-
Nontyphoid Salmonella bacteremia: age-related differences in clinical presentation, bacteriology, and outcome.Clin Infect Dis. 1999 Apr;28(4):822-7. doi: 10.1086/515186. Clin Infect Dis. 1999. PMID: 10825045
-
[Epidemiological profile of non-typhi salmonellosis in a hospital in urban Madrid (1980-1994)].Enferm Infecc Microbiol Clin. 1996 Jun-Jul;14(6):345-51. Enferm Infecc Microbiol Clin. 1996. PMID: 8756211 Review. Spanish.
-
Leuconostoc bacteremia in pediatric patients with short bowel syndrome: case series and review.Pediatr Infect Dis J. 2008 Nov;27(11):1013-9. doi: 10.1097/INF.0b013e3181792621. Pediatr Infect Dis J. 2008. PMID: 18833028 Review.
Cited by
-
Salmonella enterica bacteraemia: a multi-national population-based cohort study.BMC Infect Dis. 2010 Apr 14;10:95. doi: 10.1186/1471-2334-10-95. BMC Infect Dis. 2010. PMID: 20398281 Free PMC article.
-
Dietary rice bran promotes resistance to Salmonella enterica serovar Typhimurium colonization in mice.BMC Microbiol. 2012 Jul 4;12:71. doi: 10.1186/1471-2180-12-71. BMC Microbiol. 2012. PMID: 22583915 Free PMC article.
-
A retrospective study of secondary bacteraemia in hospitalised adults with community acquired non-typhoidal Salmonella gastroenteritis.BMC Infect Dis. 2013 Feb 27;13:107. doi: 10.1186/1471-2334-13-107. BMC Infect Dis. 2013. PMID: 23446179 Free PMC article.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical