Finding the hematopoietic stem cell niche in the placenta
- PMID: 15737922
- DOI: 10.1016/j.devcel.2005.02.005
Finding the hematopoietic stem cell niche in the placenta
Abstract
The origin of definitive hematopoiesis poses a fundamental biological question. In this issue of Developmental Cell, two groups have independently found a novel hematopoietic stem cell (HSC) niche in the extraembryonic placenta, in addition to previously identified alternative locations of hematopoiesis at different developmental stages.
Comment on
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The placenta is a niche for hematopoietic stem cells.Dev Cell. 2005 Mar;8(3):365-75. doi: 10.1016/j.devcel.2004.12.016. Dev Cell. 2005. PMID: 15737932
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The murine placenta contains hematopoietic stem cells within the vascular labyrinth region.Dev Cell. 2005 Mar;8(3):377-87. doi: 10.1016/j.devcel.2005.02.001. Dev Cell. 2005. PMID: 15737933
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