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Review
. 2005 Feb;4(2):166-7.
doi: 10.4161/cbt.4.2.1571. Epub 2005 Feb 28.

Molecular and phenotypic heterogeneity of metastatic prostate cancer

Cindy H Chau  1 , William D Figg
Affiliations
Free article
Review

Molecular and phenotypic heterogeneity of metastatic prostate cancer

Cindy H Chau et al. Cancer Biol Ther. 2005 Feb.
Free article

Abstract

Metastatic prostate cancer remains a prevalent disease in the United States that requires detailed characterization of its pathobiology. In the December 2004 issue of Cancer Research, a comprehensive study by Shah et al. demonstrated that metastatic androgen-independent prostate cancer is a collective group of diseases even within the same patient. Understanding the molecular and phenotypic determinants of this heterogeneity is essential in assessing therapeutic outcomes in the management of prostate cancer progression.

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