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. 1979 Aug;48(2):169-74.
doi: 10.1016/0030-4220(79)90056-2.

Antibody formation to dog pulp tissue altered by AH-26 sealer via the root canal

R M Block, R D Lewis, J B Sheats, S H Burke

Antibody formation to dog pulp tissue altered by AH-26 sealer via the root canal

R M Block et al. Oral Surg Oral Med Oral Pathol. 1979 Aug.

Abstract

Pulp tissue from three experimental dogs was tested for its antigenicity before and after incubation with AH-26 sealer. identical to Reactions to Arthus skin tests showed an increased response to pulp that had been incubated in AH-26, washed, and then injected, as compared with the material alone. Hemagglutinating antibody titers (1/500 to 1/800) were obtained from pulp tissue altered by AH-26. Inhibition tests showed the apecificity of the antibody to be at a dilution titer of 1:400. Therefore, a mixture of AH-26 sealer altered dog pulp tissue and rendered it antigenically active, and a specific humoral response was produced.

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