Cellular iron metabolism: mitochondria in the spotlight
- PMID: 15747401
- DOI: 10.1182/blood-2004-12-4747
Cellular iron metabolism: mitochondria in the spotlight
Abstract
New insights into cellular iron metabolism have been provided by the recognition that certain diseases are associated with mitochondrial iron overload and by the discovery of mitochondrial ferritin (MtFt) and mitochondrial iron transporters.
Comment on
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Overexpression of mitochondrial ferritin causes cytosolic iron depletion and changes cellular iron homeostasis.Blood. 2005 Mar 1;105(5):2161-7. doi: 10.1182/blood-2004-07-2722. Epub 2004 Nov 2. Blood. 2005. PMID: 15522954
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Iron trafficking in the mitochondrion: novel pathways revealed by disease.Blood. 2005 Mar 1;105(5):1867-74. doi: 10.1182/blood-2004-10-3856. Epub 2004 Nov 4. Blood. 2005. PMID: 15528311 Review.
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