Review
doi: 10.1016/0165-6147(92)90040-d.
The influence of endocardial endothelium on myocardial contraction
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- PMID: 1574807
- DOI: 10.1016/0165-6147(92)90040-d
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Review
The influence of endocardial endothelium on myocardial contraction
Trends Pharmacol Sci.
1992 Mar.
Abstract
A novel unidentified agent, provisionally named 'endocardin', has been shown to be released from endocardial endothelium. Endocardin has a unique prolonging effect on myocardial contraction. In contrast, endothelium-derived relaxing factor released from endocardial endothelium has the opposite effect of abbreviating contraction. Jerry Smith and colleagues discuss the mechanisms of action of these agents and their possible physiology and pathophysiology.
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