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Review
. 2005 Mar 3;45(5):639-42.
doi: 10.1016/j.neuron.2005.02.013.

Homing in on intracellular Abeta?

Todd E Golde  1 , Christopher Janus
Affiliations
Free article
Review

Homing in on intracellular Abeta?

Todd E Golde et al. Neuron. .
Free article

Abstract

In this issue of Neuron, a study by Billings et al. points to intracellular Abeta as a possible cause of neuronal dysfunction. In a mouse model of Alzheimer's disease, Billings et al. link appearance of intraneuronal Abeta to cognitive impairments and then show that "clearance" of intraneuronal Abeta by anti-Abeta antibodies restores cognitive deficits.

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