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. 2005 Mar;90(3):408-10.

Mutation of the prothrombin gene and thrombotic events in patients with polycythemia vera or essential thrombocythemia: a cohort study

Heinz Gisslinger, Marcus Müllner, Ingrid Pabinger, Navide Heis-Vahidi-Fard, Bettina Gisslinger, Andrea Brichta, Thomas Bachleitner-Hofmann, Christine Mannhalter
  • PMID: 15749677

Mutation of the prothrombin gene and thrombotic events in patients with polycythemia vera or essential thrombocythemia: a cohort study

Heinz Gisslinger et al. Haematologica. 2005 Mar.

Abstract

The association between a prothrombin mutation and the risk of thrombosis was analyzed in 214 patients with polycythemia vera or essential thrombocythemia. The rate for venous thrombotic events was 14.7/100 patient-years in patients with the prothrombin mutation compared to 0.8 in patients without the mutation (rate ratio 17.5).

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