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Case Reports
. 2005 Mar;43(3):1456-8.
doi: 10.1128/JCM.43.3.1456-1458.2005.

False-positive Histoplasma capsulatum Gen-Probe chemiluminescent test result caused by a Chrysosporium species

Mary E Brandt  1 , Dennis Gaunt, Naureen Iqbal, Shirley McClinton, Sarah Hambleton, Lynne Sigler
Affiliations
Case Reports

False-positive Histoplasma capsulatum Gen-Probe chemiluminescent test result caused by a Chrysosporium species

Mary E Brandt et al. J Clin Microbiol. 2005 Mar.

Abstract

We describe a case in which the Histoplasma capsulatum AccuProbe test displayed cross-reactivity with a respiratory isolate thought to be Histoplasma but not morphologically consistent with H. capsulatum. The isolate was later identified as the Chrysosporium anamorph of Nannizziopsis vriesii by sequence analysis and phenotypic data.

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Figures

FIG. 1.
FIG. 1.
(A) Slide culture of UAMH 10417 on Leonian's medium showing microconidia on the sides and termini of hyphae. (B) Slide culture of N. vriesii CANV 10351 from a reptile.
See this image and copyright information in PMC

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