doi: 10.1016/j.peptides.2004.11.009.
Isolation of trichogin, an antifungal protein from fresh fruiting bodies of the edible mushroom Tricholoma giganteum
Affiliations
- PMID: 15752570
- DOI: 10.1016/j.peptides.2004.11.009
Item in Clipboard
Isolation of trichogin, an antifungal protein from fresh fruiting bodies of the edible mushroom Tricholoma giganteum
Peptides.
2005 Apr.
Abstract
An antifungal protein was isolated from the mushroom Tricholoma giganteum var. golden blessings. The protocol included ion exchange chromatography on DEAE-cellulose, affinity chromatography on Affi-gel blue gel, ion exchange chromatography on CM-cellulose, and gel filtration by fast protein liquid chromatography on Superdex 75. The antifungal protein, designated trichogin, was unadsorbed on DEAE-cellulose but was adsorbed on Affi-gel blue gel and CM-cellulose. It exhibited antifungal activity against Fusarium oxysporum, Mycosphaerella arachidicola and Physalospora piricola. Trichogin inhibited HIV-1 reverse transcriptase with an IC50 of 83 nM.
Similar articles
-
Alveolarin, a novel antifungal polypeptide from the wild mushroom Polyporus alveolaris.Peptides. 2004 Apr;25(4):693-6. doi: 10.1016/j.peptides.2004.01.026. Peptides. 2004. PMID: 15165727
-
Pleurostrin, an antifungal peptide from the oyster mushroom.Peptides. 2005 Nov;26(11):2098-103. doi: 10.1016/j.peptides.2005.04.010. Epub 2005 Jun 6. Peptides. 2005. PMID: 15941607
-
An antifungal peptide from the coconut.Peptides. 2005 Dec;26(12):2392-6. doi: 10.1016/j.peptides.2005.05.009. Peptides. 2005. PMID: 16308082
-
Proteins with antifungal properties and other medicinal applications from plants and mushrooms.Appl Microbiol Biotechnol. 2010 Jul;87(4):1221-35. doi: 10.1007/s00253-010-2690-4. Epub 2010 Jun 8. Appl Microbiol Biotechnol. 2010. PMID: 20532758 Review.
-
Proteins of higher fungi--from forest to application.Trends Biotechnol. 2012 May;30(5):259-73. doi: 10.1016/j.tibtech.2012.01.004. Epub 2012 Feb 15. Trends Biotechnol. 2012. PMID: 22341093 Review.
Cited by
-
Bioactivities and Health Benefits of Mushrooms Mainly from China.Molecules. 2016 Jul 20;21(7):938. doi: 10.3390/molecules21070938. Molecules. 2016. PMID: 27447602 Free PMC article. Review.
-
Natural Compounds of Fungal Origin with Antimicrobial Activity-Potential Cosmetics Applications.Pharmaceuticals (Basel). 2023 Aug 23;16(9):1200. doi: 10.3390/ph16091200. Pharmaceuticals (Basel). 2023. PMID: 37765008 Free PMC article. Review.
-
Search for Proteins in the Liquid Extract of Edible Mushroom, Agaricusbisporus, and Studying their Antibacterial Effects.Iran J Pharm Res. 2012 Winter;11(1):145-50. Iran J Pharm Res. 2012. PMID: 24250435 Free PMC article.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
