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Clinical Trial
. 2005 Aug;102(8):778-82.
doi: 10.1007/s00347-005-1192-8.

[Diagnostic value of nerve fibre layer photography in glaucoma]

[Article in German]
Affiliations
Clinical Trial

[Diagnostic value of nerve fibre layer photography in glaucoma]

[Article in German]
J Herrmann et al. Ophthalmologe. 2005 Aug.

Abstract

Purpose: Primary open-angle glaucoma is characterized by a loss of retinal nerve fibres. The aim of our present study was to evaluate the diagnostic value of retinal nerve fibre layer (RNFL) photography as a routine examination for the early diagnosis of glaucomatous damage.

Methods: Between 1991 and 2000 we monitored 96 patients with ocular hypertension in a prospective study. RNFL photography was performed in 91 subjects. These photos were evaluated by two independent observers.

Results: The mean image quality of the photos was mediocre. The correlation coefficient for the intraindividual reproducibility (image quality) was 0.713-0.863 (Kendall's coefficient). For the interindividual reproducibility the correlation coefficient was 0.541-0.581 (Somers' coefficient). Regarding the evaluation "RNFL defect yes/no", the correlations were better but there was a discrepancy between the observers.

Conclusion: Quality, reproducibility and prognostic value of RNFL photography were disappointing. Although RNFL photography may be convincing and informative in several situations, it is not efficient as a routine technique for the early diagnosis of RNFL damage in glaucoma patients.

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