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. 1986 Jan;1(1):1-6.
doi: 10.3904/kjim.1986.1.1.1.

Study on the platelet factor and beta-thromboglobulin in the patients with ischemic heart disease

M H Kim, S H Huo, K S Kim, M S Kim, J S Song

Study on the platelet factor and beta-thromboglobulin in the patients with ischemic heart disease

M H Kim et al. Korean J Intern Med. 1986 Jan.

Abstract

The platelet factor 4 (PF4) and β-thromboglobulin (β-TG) were measured to evaluate the platelet activation in vivo in patients with ischemic heart disease. The results are summarized as follows:

  1. In patients with acute myocardial infarction, the PF4 and the β-TG levels were significantly higher compared to those of normal controls (P<0.005).

  2. In patients with angina pectoris, the PF4 and the β-TG levels were not signivicantly different from those of normal controls.

  3. A pattern of decline in the PF4 and the β-TG level was shown in patients with acute myocardial infarction by day 10. In conclusion, the measurement of PF4 and β-TG is a useful method to detect the platect activation in vivo in the patients with ischemic heart disease.

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Figures

Fig. 1.
Fig. 1.
Changes in PF4 after the onset of myocardial infarction The dotted line represents the level of 30 normal subjects ± 1S.D.
Fig. 2.
Fig. 2.
Changes in β-TG after the onset of myocardial infarction. The dotted line represents the level of 30 normal subjects ± 1S.D.
Fig. 3.
Fig. 3.
Correlation between PF4 and CPK levels.
Fig. 4.
Fig. 4.
Correlation between β-TG and CPK levels.
See this image and copyright information in PMC

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