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. 2005 Mar 17;7(6):1185-8.
doi: 10.1021/ol050117y.

Preparation of enamides via palladium-catalyzed amidation of enol tosylates

Artis Klapars  1 , Kevin R Campos, Cheng-Yi Chen, Ralph P Volante
Affiliations

Preparation of enamides via palladium-catalyzed amidation of enol tosylates

Artis Klapars et al. Org Lett. .

Abstract

[reaction: see text] A Pd-catalyzed coupling of enol tosylates and amides has been developed. Ligand screening revealed dipf as the most general ligand for this transformation. A variety of enol tosylates were coupled to an array of enamides in 58-97% yield.

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