Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1979 May 31;382(2):163-77.
doi: 10.1007/BF01102872.

Purification of human intestinal goblet cell antigen (GOA), its immunohistological demonstration in the intestine and in mucus producing gastrointestinal adenocarcinomas

W Rapp, M Windisch, P Peschke, K Wurster

Purification of human intestinal goblet cell antigen (GOA), its immunohistological demonstration in the intestine and in mucus producing gastrointestinal adenocarcinomas

W Rapp et al. Virchows Arch A Pathol Anat Histol. .

Abstract

Goblet cell antigen (GOA) was purified from gastric signet ring cell carcinoma. It was immunogenic and was used to produced antisera which stained goblet cells of the small and large intestine and of intestinalized gastric mucosa by indirect immunological methods. Various types of gastric and colonic cancer contained GOA. These findings demonstrate a histiogenic relationship between intestinal goblet cells, various gastrointestinal cancers and associated premalignant conditions.

PubMed Disclaimer

References

    1. Gan. 1971 Jun;62(3):171-6 - PubMed
    1. Gut. 1973 Apr;14(4):324-9 - PubMed
    1. Anal Biochem. 1972 Oct;49(2):607-9 - PubMed
    1. Immunochemistry. 1974 May;11(5):249-53 - PubMed
    1. Digestion. 1972;5(2):116-22 - PubMed

MeSH terms