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Review
. 2005 Mar 12;330(7491):594-6.
doi: 10.1136/bmj.330.7491.594.

Validity of composite end points in clinical trials

Victor M Montori  1 , Gaietà Permanyer-Miralda, Ignacio Ferreira-González, Jason W Busse, Valeria Pacheco-Huergo, Dianne Bryant, Jordi Alonso, Elie A Akl, Antònia Domingo-Salvany, Edward Mills, Ping Wu, Holger J Schünemann, Roman Jaeschke, Gordon H Guyatt
Affiliations
Review

Validity of composite end points in clinical trials

Victor M Montori et al. BMJ. .

Abstract

Use of composite end points as the main outcome in randomised trials can hide wide differences in the individual measures. How should you apply the results to clinical practice?

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Figures

Figure 1
Figure 1
Scan of heart of patient with angina: much of treatment evidence relies on composite end points
See this image and copyright information in PMC

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