Xanthoma disseminatum with bilateral epibulbar involvement

Abstract

Purpose: To describe the ocular involvement in xanthoma disseminatum.

Design: Case report and literature review.

Methods: Histopathologic study of excised conjunctival tumor and clinical follow-up.

Results: A 29-year-old woman with normal serum lipoproteins developed widespread xanthomas of the skin, throat, and episclera. There were no signs of recurrence 12 months after removal of the conjunctival xanthomas.

Conclusions: Xanthoma disseminatum is a rare condition for which there is no medical treatment. The distinction between the normolipemic xanthomatoses awaits a better understanding of their pathogenesis. Surgical removal of episcleral xanthomas can be successful, but long-term follow-up of such patients has been limited.