Review
doi: 10.1111/j.0141-9838.2004.00727.x.
The immunoepidemiology of human hookworm infection
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- PMID: 15771680
- DOI: 10.1111/j.0141-9838.2004.00727.x
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Review
The immunoepidemiology of human hookworm infection
Parasite Immunol.
2004 Nov-Dec.
Free article
Abstract
Advances in hookworm immunoepidemiology are reviewed. Recent studies demonstrate a mixed Th1/Th2 response in human hookworm infection, with immunosuppression of specific and nonspecific IFN-gamma responses. There is increasing evidence for protective immunity in human hookworm infection, including anti-larval IL-5- and IgE-dependent mechanisms, and for immunological interactions between hookworm infection and other diseases.
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