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. 2005;6(3):R29.
doi: 10.1186/gb-2005-6-3-r29. Epub 2005 Feb 15.

The Adult Mouse Anatomical Dictionary: a tool for annotating and integrating data

Affiliations

The Adult Mouse Anatomical Dictionary: a tool for annotating and integrating data

Terry F Hayamizu et al. Genome Biol. 2005.

Abstract

We have developed an ontology to provide standardized nomenclature for anatomical terms in the postnatal mouse. The Adult Mouse Anatomical Dictionary is structured as a directed acyclic graph, and is organized hierarchically both spatially and functionally. The ontology will be used to annotate and integrate different types of data pertinent to anatomy, such as gene expression patterns and phenotype information, which will contribute to an integrated description of biological phenomena in the mouse.

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Figures

Figure 1
Figure 1
Hierarchical organization of the adult mouse anatomy ontology. The hierarchy is divided into spatial and organ system components. Blocks indicate generic group terms appropriate to multiple spatial regions.
Figure 2
Figure 2
Example showing multiple hierarchical representations for a given anatomical term. The heart is represented both as (a) an organ in the thoracic cavity, and (b) as a part of the cardiovascular organ system. (c) Detail page for the term heart showing immediate substructures. Note that both spatial and functional representations contain is-a and part-of relationships.
Figure 3
Figure 3
Using the Adult Mouse Anatomical Dictionary Browser. The MGI Browser allows the user to either browse (progressively navigate through the various hierarchies) or search (enter a text string to query for terms, for example limb) within the adult mouse anatomy ontology. 'Term Detail' pages include the unique numerical identifiers (that is MA ID numbers) for each term, as well as relevant definitions and/or synonyms.

References

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