The effect of hyperosmolarity on muscle glycogen accumulation
- PMID: 1577407
- DOI: 10.1055/s-2007-1003267
The effect of hyperosmolarity on muscle glycogen accumulation
Abstract
Soleus (red) and extensor digitorum longus (white) muscles from Sprague Dawley rats were incubated with 6-14C-labelled glucose in normal and in hyperosmotic media. Hyperosmolarity decreased 6-14C-glucose incorporation into muscle glycogen in a dose dependent manner and increased glycolysis and glucose oxidation. Increased glycogenolysis rather than decreased glycogenesis was responsible for the reduction in labelled glycogen accumulation.
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