Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2005 Mar 19;330(7492):644-8.
doi: 10.1136/bmj.330.7492.644.

Monitoring in chronic disease: a rational approach

Affiliations
Review

Monitoring in chronic disease: a rational approach

Paul Glasziou et al. BMJ. .
No abstract available

PubMed Disclaimer

Figures

Fig 1
Fig 1
The five phases of treatment monitoring
Fig 2
Fig 2
Trade-off between early detection of response and predictive power for patient relevant outcomes: early changes (drug concentration or bone turnover markers) may be helpful to monitor response but may be less predictive than late markers, although the final outcome may depend on several factors and pathways

Similar articles

Cited by

References

    1. Clague HW, Twum-Barima Y, Carruthers SG. An audit of requests for therapeutic drug monitoring of digoxin: problems and pitfalls. Ther Drug Monit 1983;5: 249-54. - PubMed
    1. Chen P, Tanasijevic MJ, Schoenenberger RA, Fiskio J, Kuperman GJ, Bates DW. A computer-based intervention for improving the appropriateness of antiepileptic drug level monitoring. Am J Clin Pathol 2003;119: 432-8. - PubMed
    1. Ryan PJ, Gilbert M, Rose PE. Computer control of anticoagulant dose for therapeutic management. BMJ 1989;299: 1207-8. - PMC - PubMed
    1. Gibson PG, Wlodarczyk J, Hensley MJ, Murree-Allen K, Olson LG, Saltos N. Using quality-control analysis of peak expiratory flow recordings to guide therapy for asthma. Ann Intern Med 1995;123: 488-92. - PubMed
    1. Jannuzzi G, Cian P, Fattore C, Gatti G, Bartoli A, Monaco F, Perucca E. A multicenter randomized controlled trial on the clinical impact of therapeutic drug monitoring in patients with newly diagnosed epilepsy. The Italian TDM Study Group in Epilepsy. Epilepsia 2000;41: 222-30. - PubMed

Publication types

MeSH terms