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Review
. 2005 Apr;17(2):123-8.
doi: 10.1016/j.ceb.2005.02.009.

Linking Rap to cell adhesion

Johannes L Bos  1
Affiliations
Review

Linking Rap to cell adhesion

Johannes L Bos. Curr Opin Cell Biol. 2005 Apr.

Abstract

The small GTPase Rap1 is involved in several aspects of cell adhesion, including integrin-mediated cell adhesion and cadherin-mediated cell junction formation. Recently, several effector proteins for Rap1 have been identified providing a clear link between Rap1 and actin dynamics. Furthermore, evidence is accumulating that Rap1 functions in the spatial and temporal control of cell polarity.

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