Switching sides: transcriptional control of CD4 thymocyte lineage commitment

Comment

Rose Zamoyska. Nat Immunol. 2005 Apr.

. 2005 Apr;6(4):363-4.

doi: 10.1038/ni0405-363.

No abstract available

Comment on

The zinc finger protein cKrox directs CD4 lineage differentiation during intrathymic T cell positive selection.
Sun G, Liu X, Mercado P, Jenkinson SR, Kypriotou M, Feigenbaum L, Galéra P, Bosselut R. Sun G, et al. Nat Immunol. 2005 Apr;6(4):373-81. doi: 10.1038/ni1183. Epub 2005 Mar 6. Nat Immunol. 2005. PMID: 15750595

The zinc finger protein cKrox directs CD4 lineage differentiation during intrathymic T cell positive selection.
Sun G, Liu X, Mercado P, Jenkinson SR, Kypriotou M, Feigenbaum L, Galéra P, Bosselut R. Sun G, et al. Nat Immunol. 2005 Apr;6(4):373-81. doi: 10.1038/ni1183. Epub 2005 Mar 6. Nat Immunol. 2005. PMID: 15750595
A Fateful Decision in the Thymus Controlled by the Transcription Factor ThPOK.
Egawa T. Egawa T. J Immunol. 2021 May 1;206(9):1981-1982. doi: 10.4049/jimmunol.2100157. J Immunol. 2021. PMID: 33879577 No abstract available.
CD4-CD8 lineage commitment is regulated by a silencer element at the ThPOK transcription-factor locus.
He X, Park K, Wang H, He X, Zhang Y, Hua X, Li Y, Kappes DJ. He X, et al. Immunity. 2008 Mar;28(3):346-58. doi: 10.1016/j.immuni.2008.02.006. Immunity. 2008. PMID: 18342007
Thymus lineage commitment: a single switch.
Hedrick SM. Hedrick SM. Immunity. 2008 Mar;28(3):297-9. doi: 10.1016/j.immuni.2008.02.011. Immunity. 2008. PMID: 18342002 Review.
Do the CD4 and CD8 lineages represent parallel pathways?
Spain LM, Yelon D, Berg LJ. Spain LM, et al. Semin Immunol. 1994 Aug;6(4):213-20. doi: 10.1006/smim.1994.1028. Semin Immunol. 1994. PMID: 8000030 Review.