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. 2005 Apr;58(4):417-9.
doi: 10.1136/jcp.2004.023564.

Results of a questionnaire regarding criteria for adequacy of endometrial biopsies

V Phillips  1 , W G McCluggage
Affiliations

Results of a questionnaire regarding criteria for adequacy of endometrial biopsies

V Phillips et al. J Clin Pathol. 2005 Apr.

Abstract

Aims: Pathologists are faced with increasing numbers of endometrial biopsies containing scant tissue. Anecdotal evidence points to significant variation among pathologists regarding criteria used to assess adequacy, and no standard recommendations exist. An initial audit showing variation in endometrial biopsy adequacy reporting prompted this assessment of the criteria used by specialist gynaecological pathologists for the classification of adequacy.

Methods: A questionnaire regarding criteria used for endometrial biopsy assessment adequacy was sent to members of the British Association of Gynaecological Pathologists and the National Gynaecological Pathology External Quality Assessment Scheme (UK). One hundred and thirty questionnaires were distributed and 61 pathologists responded.

Results: The responses showed great variation in criteria used to classify endometrial biopsies as adequate. Most respondents felt it would be useful if criteria were proposed to aid this assessment.

Conclusions: Wide variation exists among specialist gynaecological pathologists regarding what constitutes an adequate endometrial biopsy. The gynaecologist should interpret the biopsy report in the light of clinical, radiological, and hysteroscopic features. The presence of scanty tissue in postmenopausal women with a thin endometrium and no focal lesion is expected, and is not a reason for repeat biopsy. Pathologists should exercise caution before classifying endometrial biopsies as inadequate, because this may have medicolegal and management implications.

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Figures

Figure 1
Figure 1
Examples of suggested alternative terminologies to inadequate or insufficient.
See this image and copyright information in PMC

References

    1. Clark TJ, Mann CH, Shah N, et al. Accuracy of outpatient endometrial biopsy in the diagnosis of endometrial hyperplasia. Acta Obstet Gynecol Scand 2001;80:784–93. - PubMed
    1. Machado F, Moreno J, Carazo M, et al. Accuracy of endometrial biopsy with the Cornier pipelle for diagnosis of endometrial cancer and atypical hyperplasia. Eur J Gynaecol Oncol 2003;24:279–81. - PubMed
    1. Archer DF, McIntyre-Seltman K, Wilborn WW Jr, et al. Endometrial morphology in asymptomatic postmenopausal women. Am J Obstet Gynecol 1991;165:317–20. - PubMed
    1. Gordon SJ, Westgate J. The incidence and management of failed pipelle sampling in a general outpatient clinic. Aust N Z J Obstet Gynaecol 1999;39:115–18. - PubMed
    1. Antoni J, Folch E, Costa J, et al. Comparison of cystopat and pipelle endometrial biopsy instruments. Eur J Obstet Gynecol Reprod Biol 1997;72:57–61. - PubMed