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Review
. 2005 Mar;18(1):30-5.
doi: 10.1053/j.semvascsurg.2004.12.009.

Causes of severe chronic venous insufficiency

Peter J Pappas  1 , Brajesh K Lal, Joaquim J Cerveira, Frank T Padberg Jr, Walter N Duran
Affiliations
Review

Causes of severe chronic venous insufficiency

Peter J Pappas et al. Semin Vasc Surg. 2005 Mar.

Abstract

A large number of adults in this country have some form of chronic venous insufficiency and a significant percentage of these have venous ulcers. The past decade has refined understanding of leukocyte-mediated injury and has elucidated the role of inflammatory processes in the dermal pathology of chronic venous insufficiency. Understanding of these pathologic cellular functions and molecular regulation of these processes is increasing.

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