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Comparative Study
. 2005 Apr;49(4):1604-7.
doi: 10.1128/AAC.49.4.1604-1607.2005.

Sensititre YeastOne caspofungin susceptibility testing of Candida clinical isolates: correlation with results of NCCLS M27-A2 multicenter study

Emilia Cantón  1 , Javier Pemán, Miguel Gobernado, Elena Alvarez, Fernando Baquero, Ramón Cisterna, Joaquina Gil, Estrella Martín-Mazuelos, Carmen Rubio, Aurora Sánchez-Sousa, Carmen Serrano
Affiliations
Comparative Study

Sensititre YeastOne caspofungin susceptibility testing of Candida clinical isolates: correlation with results of NCCLS M27-A2 multicenter study

Emilia Cantón et al. Antimicrob Agents Chemother. 2005 Apr.

Abstract

The ability of Sensititre YeastOne to discriminate isolates with reduced caspofungin susceptibility was determined against 36 Candida spp. (6 with a known FKS1 mutation). Results were compared with those of M27-A2. The MIC endpoint was 100% growth inhibition. Overall agreement (+/-2 log2) was 87.16%. Sensititre YeastOne detected strains with reduced caspofungin susceptibility.

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References

    1. Barry, A. L., M. A. Pfaller, S. D. Brown, A. Espinel-Ingroff, M. A. Ghannoum, C. Knapp, R. P. Rennie, J. H. Rex, and M. G. Rinaldi. 2000. Quality control limits for broth microdilution susceptibility tests of ten antifungal agents. J. Clin. Microbiol. 38:3457-3459. - PMC - PubMed
    1. Bartizal, C., and F. C. Odds. 2003. Influences of methodological variables on susceptibility testing of caspofungin against Candida species and Aspergillus fumigatus. Antimicrob. Agents Chemother. 47:2100-2107. - PMC - PubMed
    1. Cantón, E., J. Pemán, A. Carrillo-Muñoz, A. Orero, P. Ubeda, A. Viudes, and M. Gobernado. 1999. Fluconazole susceptibilities of bloodstream Candida sp. isolates as determined by National Committee for Clinical Laboratory Standards method M27-A and two other methods. J. Clin. Microbiol. 37:2197-2200. - PMC - PubMed
    1. Douglas, C. M., J. A. D'Ippolito, G. J. Shei, M. Meinz, J. Onishi, J. A. Marrinan, W. Li, G. K. Abruzzo, A. Flattery, K. Bartizal, A. Mitchell, and M. B. Kurtz. 1997. Identification of the FKS1 gene of Candida albicans as the essential target of 1,3-β-d-glucan synthase inhibitors. Antimicrob. Agents Chemother. 41:2471-2479. - PMC - PubMed
    1. Espinel-Ingroff, A. 1998. Comparison of in vitro activities of the new triazole SCH56592 and the echinocandins MK-0991 (L-743,872) and LY303366 against opportunistic filamentous and dimorphic fungi and yeasts. J. Clin. Microbiol. 36:2950-2956. - PMC - PubMed

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