Effects on immune response of antidiabetic ingredients from white-skinned sweet potato (Ipomoea batatas L.)
- PMID: 15797679
- DOI: 10.1016/j.nut.2004.11.001
Effects on immune response of antidiabetic ingredients from white-skinned sweet potato (Ipomoea batatas L.)
Abstract
Objectives: The present report describes the effects of antidiabetic ingredients from white-skinned sweet potato (AWSSP) on the immune response of human cells.
Methods: We studied the effects of inactive Staphylococcus aureus cells coated with AWSSP on phagocytic activity, phagosome-lysosome fusion, and superoxide anion release by human leukocytes in vitro.
Results: AWSSP increased phagocytic activity and phagosome-lysosome fusion in neutrophils and monocytes in a dose-dependent manner. In contrast, AWSSP had no significant effect on superoxide anion release (O2-) from human neutrophils.
Conclusions: These results show that AWSSP is useful in the prevention and improvement of diabetic symptoms by stimulating human immunity and that Ipomoea batatas L. is a beneficial food because it increases immune activity in addition to its antidiabetic effects.
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