"Proximal-type" and classic epithelioid sarcomas represent a clinicopathologic continuum: case report
- PMID: 15803217
- DOI: 10.1007/s10024-004-7086-y
"Proximal-type" and classic epithelioid sarcomas represent a clinicopathologic continuum: case report
Abstract
We report a case of an epithelioid sarcoma that occurred in the right hand of a 14-year-old boy and had the "proximal-type" morphology and a complex, near-tetraploid karyotype. The tumor metastasized to the lungs, where the morphology was typical for the classic epithelioid sarcoma. Based on the morphologic and cytogenetic findings in this case, we suggest that the proximal-type and the classic epithelioid sarcomas are not distinct entities but represent a continuum.
Similar articles
-
Epithelioid variant of myxofibrosarcoma: expanding the clinicomorphologic spectrum of myxofibrosarcoma in a series of 17 cases.Am J Surg Pathol. 2007 Jan;31(1):99-105. doi: 10.1097/01.pas.0000213379.94547.e7. Am J Surg Pathol. 2007. PMID: 17197925
-
Proximal type epithelioid sarcoma of the scrotum: a source of diagnostic confusion that needs immediate attention.Eur Urol. 2006 Feb;49(2):406-7. doi: 10.1016/j.eururo.2005.09.020. Epub 2005 Nov 7. Eur Urol. 2006. PMID: 16343734
-
Epithelioid sarcoma in children and adolescents: a report from the Italian Soft Tissue Sarcoma Committee.Cancer. 2006 Feb 1;106(3):708-17. doi: 10.1002/cncr.21630. Cancer. 2006. PMID: 16353216
-
Malignant teratoma of the thyroid with primitive neuroepithelial and mesenchymal sarcomatous components.Ann Diagn Pathol. 2001 Oct;5(5):285-92. doi: 10.1053/adpa.2001.27918. Ann Diagn Pathol. 2001. PMID: 11598856 Review.
-
Undifferentiated sarcoma: does it exist? A clinicopathologic study of 7 pediatric cases and review of literature.Hum Pathol. 2009 Nov;40(11):1600-10. doi: 10.1016/j.humpath.2009.04.013. Epub 2009 Aug 3. Hum Pathol. 2009. PMID: 19647855 Review.
Cited by
-
Epithelioid Sarcoma: Opportunities for Biology-Driven Targeted Therapy.Front Oncol. 2015 Aug 17;5:186. doi: 10.3389/fonc.2015.00186. eCollection 2015. Front Oncol. 2015. PMID: 26347853 Free PMC article. Review.
-
Epithelioid Sarcoma-From Genetics to Clinical Practice.Cancers (Basel). 2020 Jul 29;12(8):2112. doi: 10.3390/cancers12082112. Cancers (Basel). 2020. PMID: 32751241 Free PMC article. Review.
-
Ipsilateral breast metastasis after axillary dissection caused by epithelioid sarcoma: a case report and pathological investigation.Diagn Pathol. 2019 Oct 15;14(1):111. doi: 10.1186/s13000-019-0888-z. Diagn Pathol. 2019. PMID: 31615564 Free PMC article.
-
CHIR99021, trough GSK-3β Targeting, Reduces Epithelioid Sarcoma Cell Proliferation by Activating Mitotic Catastrophe and Autophagy.Int J Mol Sci. 2021 Oct 15;22(20):11147. doi: 10.3390/ijms222011147. Int J Mol Sci. 2021. PMID: 34681807 Free PMC article.
-
The evolving management of epithelioid sarcoma.Eur J Cancer Care (Engl). 2021 Nov;30(6):e13489. doi: 10.1111/ecc.13489. Epub 2021 Jul 18. Eur J Cancer Care (Engl). 2021. PMID: 34278633 Free PMC article. No abstract available.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical