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Review
. 2005 Jul;23(3):196-201.
doi: 10.1007/s00345-004-0470-4. Epub 2005 Apr 2.

Immunotherapy in metastatic renal cell carcinoma

Karl Rohrmann  1 , Michael Staehler, Nikolas Haseke, Alexander Bachmann, Christian G Stief, Michael Siebels
Affiliations
Review

Immunotherapy in metastatic renal cell carcinoma

Karl Rohrmann et al. World J Urol. 2005 Jul.

Abstract

Metastatic renal cell carcinoma has a poor prognosis. Conventional therapies such as chemotherapy, radiation or hormonal treatment have hardly any effect on the progression of this disease. As renal cell carcinoma seems to be an immunogenic tumor, several immunotherapeutic approaches with different response rates have been developed since the early 1990s. We present an overview of various immunotherapeutic approaches such as cytokine-based regimes, with and without different cytotoxic chemotherapy, of metastatic renal cell carcinoma. In addition, local therapies (e.g. inhalation of interleukin-2) are reviewed.

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