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. 2005 Apr;43(4):1600-3.
doi: 10.1128/JCM.43.4.1600-1603.2005.

Colonization of human immunodeficiency virus-infected outpatients in Taiwan with Candida species

Chien-Ching Hung  1 , Yun-Liang Yang, Tsai-Ling Lauderdale, L Clifford McDonald, Chin-Fu Hsiao, Hsiao-Hsu Cheng, Yong An Ho, Hsiu-Jung Lo
Affiliations

Colonization of human immunodeficiency virus-infected outpatients in Taiwan with Candida species

Chien-Ching Hung et al. J Clin Microbiol. 2005 Apr.

Abstract

To understand the Candida colonization of human immunodeficiency virus (HIV)-infected outpatients in Taiwan, we have conducted a prospective cohort study of Candida colonization and its risk factors at the National Taiwan University Hospital from 1999 to 2002. More than 50% of the patients were colonized with Candida species, and 12% developed symptomatic candidiasis. Patients colonized with fluconazole-resistant strains of Candida species had a higher prevalence of candidiasis than those colonized with susceptible strains. Our analysis found that antibiotic treatment and lower CD4(+) counts (<200 cells/mm(3)) increased the rate of oropharyngeal candidiasis in HIV-infected patients, while antiretroviral therapy protected patients from the development of candidiasis.

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