doi: 10.1109/tnb.2004.842495.
Poisson-Nernst-Planck theory approach to the calculation of current through biological ion channels
Affiliations
- PMID: 15816174
- DOI: 10.1109/tnb.2004.842495
Item in Clipboard
Poisson-Nernst-Planck theory approach to the calculation of current through biological ion channels
IEEE Trans Nanobioscience.
2005 Mar.
Abstract
The Poisson-Nernst-Planck (PNP) theory of electro-diffusion is reviewed. Techniques for numerical solution of the three-dimensional PNP equations are summarized, and several illustrative applications to ion transport through protein channels are presented. Strengths and weaknesses of the theory are discussed, as well as attempts to improve it via increasingly realistic evaluation of the force acting on each ion due to the protein/membrane environment.
Similar articles
-
The role of the dielectric barrier in narrow biological channels: a novel composite approach to modeling single-channel currents.Biophys J. 2003 Jun;84(6):3646-61. doi: 10.1016/S0006-3495(03)75095-4. Biophys J. 2003. PMID: 12770873 Free PMC article.
-
Voltage-gated ion channels.IEEE Trans Nanobioscience. 2005 Mar;4(1):34-48. doi: 10.1109/tnb.2004.842463. IEEE Trans Nanobioscience. 2005. PMID: 15816170 Review.
-
Physical descriptions of experimental selectivity measurements in ion channels.Eur Biophys J. 2002 Oct;31(6):454-66. doi: 10.1007/s00249-002-0239-x. Epub 2002 Jul 16. Eur Biophys J. 2002. PMID: 12355255
-
Poisson-Boltzmann-Nernst-Planck model.J Chem Phys. 2011 May 21;134(19):194101. doi: 10.1063/1.3581031. J Chem Phys. 2011. PMID: 21599038 Free PMC article.
-
Gramicidin channels.IEEE Trans Nanobioscience. 2005 Mar;4(1):10-20. doi: 10.1109/tnb.2004.842470. IEEE Trans Nanobioscience. 2005. PMID: 15816168 Review.
Cited by
-
Molecular dynamics simulation of the antiamoebin ion channel: linking structure and conductance.Biophys J. 2011 May 18;100(10):2394-402. doi: 10.1016/j.bpj.2011.03.054. Biophys J. 2011. PMID: 21575573 Free PMC article.
-
Variational multiscale models for charge transport.SIAM Rev Soc Ind Appl Math. 2012;54(4):699-754. doi: 10.1137/110845690. Epub 2012 Nov 8. SIAM Rev Soc Ind Appl Math. 2012. PMID: 23172978 Free PMC article.
-
A Focus on Two Electrokinetics Issues.Micromachines (Basel). 2020 Nov 24;11(12):1028. doi: 10.3390/mi11121028. Micromachines (Basel). 2020. PMID: 33255260 Free PMC article.
-
Interacting ions in biophysics: real is not ideal.Biophys J. 2013 May 7;104(9):1849-66. doi: 10.1016/j.bpj.2013.03.049. Biophys J. 2013. PMID: 23663828 Free PMC article. Review.
-
Electrophysiological Properties from Computations at a Single Voltage: Testing Theory with Stochastic Simulations.Entropy (Basel). 2021 May 6;23(5):571. doi: 10.3390/e23050571. Entropy (Basel). 2021. PMID: 34066581 Free PMC article.
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Miscellaneous
