Remote control of fruit fly behavior

Abstract

Electrical stimulation of neurons in the central nervous system of awake, behaving animals offers the ultimate test to determine whether the activation of specific neurons is sufficient to elicit perception, motor activity, or other behaviors. In this issue of Cell, Lima and Miesenböck (Lima and Miesenböck, 2005) dump the stimulating electrode in favor of a new remote control system to excite specific neurons--light activation of transgenically supplied ion channels.