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Review
. 2005 Apr 8;121(1):9-12.
doi: 10.1016/j.cell.2005.03.021.

Melanocyte stem cell maintenance and hair graying

Eiríkur Steingrímsson  1 , Neal G Copeland, Nancy A Jenkins
Affiliations
Free article
Review

Melanocyte stem cell maintenance and hair graying

Eiríkur Steingrímsson et al. Cell. .
Free article

Abstract

Hair graying is an obvious sign of human aging, yet little was known about its causes. Two recent papers provide compelling evidence that hair graying is due to incomplete melanocyte stem cell maintenance and identify Pax3 and Mitf as key molecules that help regulate the balance between melanocyte stem cell maintenance and differentiation.

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