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Review
. 2005 Apr 12;15(7):R249-52.
doi: 10.1016/j.cub.2005.03.024.

Sex chromosome inactivation: the importance of pairing

Jeannie T Lee  1
Affiliations
Free article
Review

Sex chromosome inactivation: the importance of pairing

Jeannie T Lee. Curr Biol. .
Free article

Abstract

In mammals, the process of making sperm is marked by inactivation of sex chromosomes. Why and how does this happen? The answer apparently lies in whether a chromosome finds a pairing partner. Similar mechanisms in mold and worms reveal a surprising and recurrent theme throughout evolution.

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