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. 2005 May 1;40(9):1368-71.
doi: 10.1086/429317. Epub 2005 Mar 23.

Characterization and management of paradoxical upgrading reactions in HIV-uninfected patients with lymph node tuberculosis

Charlotte R Hawkey  1 , Timothy Yap, Janis Pereira, David A J Moore, Robert N Davidson, Geoffrey Pasvol, Onn Min Kon, Robert A Wall, Robert J Wilkinson
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Characterization and management of paradoxical upgrading reactions in HIV-uninfected patients with lymph node tuberculosis

Charlotte R Hawkey et al. Clin Infect Dis. .

Abstract

In a retrospective analysis, paradoxical deterioration of lymph node tuberculosis in human immunodeficiency virus-uninfected patients was common, occurring in 25 (23%) of 109 patients after treatment had been given for a median of 46 days (interquartile range, 21-139 days) and persisting for a median of 67.5 days (interquartile range, 34-111 days). We found no association between the use of steroids and the duration of reaction.

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