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. 2005 Apr;5(4):729-33.
doi: 10.1021/nl050175c.

Programmable DNA self-assemblies for nanoscale organization of ligands and proteins

Sung Ha Park  1 , Peng Yin, Yan Liu, John H Reif, Thomas H LaBean, Hao Yan
Affiliations

Programmable DNA self-assemblies for nanoscale organization of ligands and proteins

Sung Ha Park et al. Nano Lett. 2005 Apr.

Abstract

We demonstrate the precise control of periodic spacing between individual protein molecules by programming the self-assembly of DNA tile templates. In particular, we report the application of two self-assembled periodic DNA structures, two-dimensional nanogrids, and one-dimensional nanotrack, as template for programmable self-assembly of streptavidin protein arrays with controlled density.

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