Comment on

• DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis.

  Bartkova J, Horejsí Z, Koed K, Krämer A, Tort F, Zieger K, Guldberg P, Sehested M, Nesland JM, Lukas C, Ørntoft T, Lukas J, Bartek J. Bartkova J, et al. Nature. 2005 Apr 14;434(7035):864-70. doi: 10.1038/nature03482. Nature. 2005. PMID: 15829956
• Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions.

  Gorgoulis VG, Vassiliou LV, Karakaidos P, Zacharatos P, Kotsinas A, Liloglou T, Venere M, Ditullio RA Jr, Kastrinakis NG, Levy B, Kletsas D, Yoneta A, Herlyn M, Kittas C, Halazonetis TD. Gorgoulis VG, et al. Nature. 2005 Apr 14;434(7035):907-13. doi: 10.1038/nature03485. Nature. 2005. PMID: 15829965