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. 1979 Oct;91(4):587-604.
doi: 10.7326/0003-4819-91-4-587.

NIH conference. Systemic lupus erythematosus: evolving concepts

NIH conference. Systemic lupus erythematosus: evolving concepts

J L Decker et al. Ann Intern Med. 1979 Oct.

Abstract

Systemic lupus erythematosus, a disease of unknown cause and protean manifestations, continues to excite substantial investigational interest. These papers bring together recent advances in concepts of its immunopathogenesis, evidence for a major genetic role in the causation of the process, developing systems for the morphologic assessment of its often fatal nephritis, and data from ongoing trials of cytotoxic drugs in its management.

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