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Review
. 2005 Apr 29;234(1-2):81-6.
doi: 10.1016/j.mce.2004.09.008.

Anti-Müllerian hormone and folliculogenesis

Jenny A Visser  1 , Axel P N Themmen
Affiliations
Review

Anti-Müllerian hormone and folliculogenesis

Jenny A Visser et al. Mol Cell Endocrinol. .

Abstract

This paper reviews the role of anti-Müllerian hormone, a member of the TGF(beta) family signaling through a BMP-like pathway, in the ovary. In vivo and in vitro studies showed that AMH has an inhibitory effect on primordial follicle recruitment and it decreases the sensitivity of follicles for the FSH-dependent selection for dominance. Besides its functional role in the ovary, AMH serum level serves as an excellent candidate marker of ovarian reserve.

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