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Comparative Study
. 2005 May 2;15(9):2381-4.
doi: 10.1016/j.bmcl.2005.02.090.

New pyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-ones as potent and selective PDE5 inhibitors

Joan Feixas  1 , Maria Paola Giovannoni, Claudia Vergelli, Amadeu Gavaldà, Nicoletta Cesari, Alessia Graziano, Vittorio Dal Piaz
Affiliations
Comparative Study

New pyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-ones as potent and selective PDE5 inhibitors

Joan Feixas et al. Bioorg Med Chem Lett. .

Abstract

A series of potent PDE5 inhibitors with high selectivity versus PDE6 isoenzymes was identified.

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